- Title
- A virtual audit system for intensity-modulated radiation therapy credentialing in Japan Clinical Oncology Group clinical trials: A pilot study
- Creator
- Nakamura, Mitsuhiro; Zhou, Dejun; Miles, Elizabeth; Lehmann, Joerg; Andratschke, Nicolaus; Kry, Stephen; Ishikura, Satoshi; Mizowaki, Takashi; Nishio, Teiji; Minemura, Toshiyuki; Kito, Satoshi; Okamoto, Hiroyuki; Tohyama, Naoki; Kurooka, Masahiko; Kumazaki, Yu; Ishikawa, Masayori; Clark, Catharine H.
- Relation
- Journal of Applied Clinical Medical Physics Vol. 24, Issue 6, no. e14040
- Publisher Link
- http://dx.doi.org/10.1002/acm2.14040
- Publisher
- John Wiley & Sons, Inc.
- Resource Type
- journal article
- Date
- 2023
- Description
- Purpose: The Medical Physics Working Group of the Radiation Therapy Study Group at the Japan Clinical Oncology Group is currently developing a virtual audit system for intensity-modulated radiation therapy dosimetry credentialing. The target dosimeters include films and array detectors, such as ArcCHECK (Sun Nuclear Corporation, Melbourne, Florida, USA) and Delta4 (ScandiDos, Uppsala, Sweden). This pilot study investigated the feasibility of our virtual audit system using previously acquired data. Methods: We analyzed 46 films (32 and 14 in the axial and coronal planes, respectively) from 29 institutions. Global gamma analysis between measured and planned dose distributions used the following settings: 3%/3 mm criteria (the dose denominator was 2 Gy), 30% threshold dose, no scaling of the datasets, and 90% tolerance level. In addition, 21 datasets from nine institutions were obtained for array evaluation. Five institutions used ArcCHECK, while the others used Delta4. Global gamma analysis was performed with 3%/2 mm criteria (the dose denominator was the maximum calculated dose), 10% threshold dose, and 95% tolerance level. The film calibration and gamma analysis were conducted with in-house software developed using Python (version 3.9.2). Results: The means ± standard deviations of the gamma passing rates were 99.4 ± 1.5% (range, 92.8%–100%) and 99.2 ± 1.0% (range, 97.0%–100%) in the film and array evaluations, respectively. Conclusion: This pilot study demonstrated the feasibility of virtual audits. The proposed virtual audit system will contribute to more efficient, cheaper, and more rapid trial credentialing than on-site and postal audits; however, the limitations should be considered when operating our virtual audit system.
- Subject
- gamma analysis; IMRT dosimetry credentialing; JCOG; prospective trials; virtual audit
- Identifier
- http://hdl.handle.net/1959.13/1483141
- Identifier
- uon:51080
- Identifier
- ISSN:1526-9914
- Rights
- X
- Language
- eng
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